Daniel F. Moriarty

Associate Professor of Chemistry and Biochemistry

Phone: (518) 783‑2472
Email: dmoriarty@siena.edu


Degrees:

Ph.D. Chemistry SUNY Stony Brook
M.S. Chemistry SUNY Stony Brook
B.S. Chemistry Siena College

Bio:

Born and raised in Delmar, NY, Dr. Moriarty received a B.S. in Chemistry from Siena College before moving to Stony Brook University. He studied under Dr. Daniel Raleigh and received his Ph.D. in Chemistry. He then spent three years at Rensselaer as a Post-Doc working with Dr. Wilfredo Colon in the Chemistry and Chemical Biology Department before coming back to his alma matter and joining the faculty.

What I love about Siena:

The school has a strong sense of community. We have a strong focus on undergraduate education, both in the classroom and in the lab. The classes are small enough that I get to know all the students. I can see what they are doing well on, and what they need a little extra help with.

My Favorite courses to teach are:

-General Chemistry. This class not only lays the foundation of the remianing chemistry courses, but since many students take the course in their first year, it helps prepare them for life in college.
-Physical Biochemistry. Most of our chemistry majors do not take many biology courses while at Siena. This gives me a chace to show the students biological application of the chemical principles they have learned. It is also a class that the seniors take, so I get to see the students at both the beginning and the end of their career at Siena.

Professional Experience:

Associate Professor, Chemistry & Biochemistry Siena College 2008 - Now
Visiting Research Associate, Chemistry & Chemical Biology RPI 2008 - 2009
Assistant Professor, Chemistry & Biochemistry Siena College 2003 - 2008
Visiting Assistant Professor, Chemistry Siena College 2002 - 2003
Post Doctoral Research Fellow, Biochemistry RPI 1999 - 2002

Why I chose Siena:

Having gone to college at Siena, I knew the environment was a great fit for me. I really enjoy the 1-on-1 interaction with the students and our great facilities. The people really make the School of Science and Siena a special place. Once I walked back on campus for the interview, I knew I had found the place for me.

Office Hours:

MON: 01:30 PM-02:30 PM
TUE:
WED: 01:30 PM-02:30 PM
THU: 09:30 AM-11:30 AM
FRI: 01:30 PM-02:30 PM

My current research:

-Protein Folding
-Amyloid Formation and Disease
-Astrobiology
-Molecules with Antibacterial Properties from Natural Sources

My teaching philosophy:

One thing I try to do is to make the material interesting for the students regardless of major. Teaching is a partnership, and while it is ultimately the student’s responsibility to learn the material, I believe there is also a duty of the professor to help the students along and to make the subject matter accessible and engaging. One important way I do this is in every lecture to show the students the relevancy of the material to everyday life. Why does Tums or Milk of Magnesia help settle an upset stomach? Simple acid-base chemistry. What causes Alzheimer’s Disease and Type II Diabetes? Misfolded proteins. Why does cooking an egg cause it to become harder? Thermally denatured proteins. Bringing the student’s own experiences into the lecture allows them to take more out of the material. I also believe it’s important for the students to see exactly how scientists have arrived at their discoveries over the years. This gives them a better understanding of how scientists conduct their work, as well as an appreciation for the many hurtles that we have yet to overcome.


Using iPads in the Chemistry Classroom: Focusing on Paperless Education and Identification and Directed use of Pedagogically Directed Applications
Chemical Educator
2013
A Truncated Peptide Model of the Mutant P61A FIS Forms a Stable Dimer
Biochem Biophys Acta
2007
Equilibrium denaturation studies of the E. coli factor for inversion stimulation: Implications for in vivo function
Protein Science, vol. 11
2002
Role of Local Interactions in Stabilizing the 6-120 Disulfide Bond in á-lactalbumin: Implications for Formation of the Molten Globule State
Biochem Biophys Acta, vol. 1476
2000
Analysis of Sequential Proline Substitutions on Amyloid Formation in the Polypeptide Hormone Amylin
Biochemistry, vol. 38
1999
A Role for the C-terminus of calcitonin in Aggregation and Gel Formation: A Comparative Study of C-terminal Fragments of Human and Salmon Calcitonin
Biochem. Biophys. Res. Comm, vol. 245
1998
Amyloid Proteins: The Beta Sheet Conformation and Disease
Wiley-VCH
2005
Practical Limitations on Matrix-assisted laser desorption ionization time-of-flight mass spectroscopy (MALDI-TOFMS)
2014
Academic Celebration Siena College, Loudonville, New York
Isolation and Characterization of Antibacterial Molecules in Different Species of Cinnamon
2014
Siena College Summer Research Symposium, Loudonville, New York
Isolation and Identification of Antibacterial Compounds in Sage (Salvia officinalis) and Rosemary (rosmarinus officinalis)
2014
Siena College Academic Celebration, Loudonville, New York
Isolation and Characterization of Water Soluble and Organic Soluble of Antibacterial Compounds in Plants using Mass Spectrometry
2014
Eastern New York ACS Undergraduate Research Poster Session, Loudonville, New York
Investigation into the Energetic Processes of Peptide Bond Formation on Prebiotic Earth
2014
Eastern New York ACS Undergraduate Research Poster Session, Loudonville, New York
Isolation and characterization of water-soluble and organic-soluble antibacterial molecules in plants using mass spectrometry
2014
248 American Chemical Society National Meeting and Exposition, San Francisco, California
Isolation and Characterization of Water Soluble Antibacterial Compounds in Sage and Rosemary
2013
Siena College Summer Research Symposium, Loudonville, New York
Designing a Lab to Study the Comparative Proteomics of Fish using Gel Electrophoresis Techniques
2013
Siena College Academic Celebration, Loudonville, New York
Quantifying Protein Content in Various Food Types via Spectroscopic Analysis and High Performance Liquid Chromatography
2013
Siena College Academic Celebration, Loudonville, New York
Isolation of Antibacterial Molecules from Garlic and Sage against Staphylococcus aureus
2013
Eastern New York ACS Undergraduate Research Poster Session, Loudonville, New York
Direct Oxidative Induced Folding of ?-conotoxin ImI
2012
Siena College Academic Celebration, Loudonville, New York
Determining the Characteristics of Proteins Using Differential Scanning Calorimetry
2012
Siena College Academic Celebration, Loudonville, New York
Using iPads in the chemistry classroom: Steps toward a fully paperless classroom
2012
243rd American Chemical Society National Meeting and Exposition, San Diego, California
Staphylococcus aureus cell wall proteins targeted by antibacterial plant extracts
2012
243rd American Chemical Society National Meeting & Exposition, San Diego, California
Staphylococcus aureus cell wall proteins targeted by antibacterial plant extracts
2012
Eastern New York ACS Undergraduate Research Poster Session, Loudonville, New York
Isolation of Antibacterial Molecules from Garlic and Sage against Staphylococcus aureus
2012
244th American Chemical Society National Meeting and Exposition, Philadelphia, Pennsylvania
Inhibiting the Growth of Escherichia coli and Staphylococcus aureus using Geranium Leaf Extracts
2011
Siena College Academic Celebration, Loudonville, New York
Isolation of Kinetic Stability in Proteins via Two-Dimensional Polyacrylamide Gel Electrophoresis
2011
Siena College Academic Celebration, Loudonville, New York
Calculation of Enthalpy Changes for a Series of Proteins Using Differential Scanning Calorimetry
2011
Siena College Academic Celebration, Loudonville, New York
Solvent-Induced Folding and Isolation via HPLC of ?-conotoxin ImI
2011
Siena College Academic Celebration, Loudonville, New York
Testing for the Presence of Kinetic Stability in Proteins in Various Foods Using 2-D Gel Electrophoresis
2010
Eastern New York ACS Undergraduate Research Poster Session, Loudonville, New York
Testing for the Presence of Kinetic Stability in Proteins in Various Foods Using 2-D Gel Electrophoresis
2010
Academic Celebration Siena College, Loudonville, New York
alpha-conotoxin ImI disulfide Bonding
2010
Academic Celebration Siena College, Loudonville, New York
Thermodynamic Analysis of Protein Unfolding and Identification: DSC Method
2010
Academic Celebration Siena College, Loudonville, New York
Thermodynamic Analysis of Protein Unfolding and Identification: DSC Method
2010
Eastern NY ACS Undergraduate Research Symposium, Loudonville, New York
Antibiotic Activity of Plant Extracts on E. coli (gram negative rod) and Staphlococcus Aureus (gram positive coccus)
2009
Siena College Academic Celebration, Loudonville, New York
Formation of disulfide bonds in ?-conotoxin ImI"
2008
Siena College Academic Celebration, Loudonville, New York
The Effect of Organic Cosolvents on the Folding of ?-conotoxin ImI
2007
Siena College Academic Celebration, Loudonville, New York
FIS project
2007
Siena College Academic Celebration, Loudonville, New York
The Core of Factor for Inversion Stimulation Forms a Stable Structure: A Model for the Dimeric Intermediate of P61A Fis
2002
224th American Chemical Society National Meeting, Boston, Massachusetts
Peptide Fragments From the DNA Binding Protein FIS: Influence of Proline on Secondary Structure
2001
6th John Hopkins Folding Meeting, Berkeley Springs, West Virginia
Peptide Models of Amyloid Formation by Amylin
1999
13th Symposium of the Protein Society, Boston, Massachusetts